Sri Chandana Kanchibhotla

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DCRC role / affiliation

DCRC-ABC, Research Student

Other roles / affiliations



In 2015, Sri Chandana Kanchibhotla successfully completed her Masters investigating the genetics of the white matter structure, the corpus callosum, in the ageing brain.  The corpus callosum is an important brain structure responsible for communication between the two hemispheres of the brain, which undergoes atrophy with ageing.  Changes in the corpus callosum have been associated with age-related cognitive impairment and neurodegenerative disease, including dementia.  Neuroimaging data from OATS (Older Adult Twin Study) was used to extract information regarding the integrity of the microstructure of the corpus callosum.  Heritability analyses were undertaken, which showed that most measures of the integrity of the corpus callosum microstructure were heritable.  

Masters Thesis: "Investigating the genetics of microstructure of the corpus callosum in the ageing brain"