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A tale of three cities - comparison of the Memory and Ageing Sydney (MAS), and Australian Imaging Biomarker and Lifestyle (AIBL) studies

Prof Henry Brodaty, Prof Perminder Sachdev, Prof David Ames, Dr Simone Reppermund
Research Centre DCRC Assessment and Better Care
Partner Institution Centre-based
Project Description

The aim of this project is to enhance prevention of cognitive decline by building on data from two large epidemiological studies which each have been assessing over 1000 persons to determine predictors of healthy and pathological cognitive ageing.

This project will compare data of people with no cognitive impairment (NCI) and mild cognitive impairment (MCI) in order to:

i) Determine population representativeness of the samples;

ii) Determine whether differences in recruitment affect findings from the two studies;

iii) Compare normal values in three Australian sites;

iv) Test robustness of findings about lifestyle factors;

v) Examine neuropsychological test performances;

vi) Compare rates of decline;

vii) Conduct collaborative work on imaging; and

viii) Conduct collaborative work on proteomics.

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