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Research Centre DCRC Assessment and Better Care
Partner Institution Centre-based
Project Description

Dementia is associated with a range of longitudinal outcomes in addition to cognitive decline. These outcomes include neuropsychiatric symptoms, institutionalisation, and death. Accurate knowledge of these outcomes is important for planning purposes and for providing patients with a prognosis. The project has two parts.

The first part examines the course of neuropsychiatric symptoms in patients with dementia. As mild cognitive impairment (MCI) may constitute an early stage of dementia in some patients, the project also examines the course of neuropsychiatric symptoms in this population and considers if these symptoms predict conversion to dementia.

The second part of the project examines predictors of the time until institutionalisation and death in patients with dementia.

Participants were recruited from nine memory clinics around Australia and followed for three years. Participants included 779 patients with dementia and 185 patients with MCI at baseline. At six time points, participants or their carers completed measures of neuropsychiatric symptoms, cognition, functional ability, dementia severity, and medication.

These data will be used to determine the course of neuropsychiatric symptoms over time. The data will also be used to determine predictors of institutionalisation and death in patients with dementia, and predictors of conversion to dementia in patients with MCI.

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