Researchers in the United States have found that a drug commonly used to treat cancer may be capable of rapidly clearing amyloid plaques, one of the key hallmarks of Alzheimer's disease, in mice. The scientists believe that the drug naturally interacts with brain cells to enhance the brain's regular mechanisms to remove amyloid.


The scientists report that the area affected by amyloid plaques was reduced by 50% within 72 hours of treatment commencing and that after 20 days of treatment mice showed improved performance on a basic memory task.

The full article is available for free viewing via the link below:

Science: ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD
Mouse Models

For a detailed press report please see the link below:
Huffington Post

 

 

Other stories from this edition of Dementia Research News:

Director's report and welcome from Prof Elizabeth Beattie

Examining the use of the Aged Care Funding Instrument (ACFI)

The use of biomarkers for Alzheimer's disease

Pain and Pain Management for RACF and Community Settings

 

News in brief:

Diagnosing mild cognitive impairment in linguistic minorities

Scholarship opportunity with the DCRC

Managing Depression Growing Older

Drug reduces amyloid plaques in mice

Self-harm in older adults

Save the date: DCRC National Dementia Research Forum